袁P

研發長Provost):

袁行修 教授Prof. Shyng-Shiou ,Yuan

 

聯絡方式:

 電話 (Tel)886-7-312-1101 分機2300

 傳真 (FAX)886-7-322-3170

  E-mail: yuanssf@kmu.edu.tw

    807高雄市十全一路100號勵學大樓三樓研究發展處

  No.100,Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

 

現任:

     高雄醫學大學研究發展處 研發長 (2021/8~)

     高雄醫學大學醫學研究所 教  授 (2019/2~)

 

 學歷:

       德州大學    分子醫學研究所       博士 (1995~1999)

     高雄醫學院  醫學研究所臨床醫學組  碩士 (1988~1992)

     高雄醫學院  醫學系               學士 (1978~1985)

 

   經歷:

1

教授 Professor - 醫學研究所 Graduate Institute of Medicine

1080201 -  

2

教授 Professor - 婦產學科 Department of Obstetrics & Gynecology

1020201 - 1080131

3

副教授 Associate Professor - 婦產科學 Obstetrics & Gynecology

0920801 - 0930329

4

助理教授 Assistant Professor - 婦產科學 Obstetrics & Gynecology

0881101 - 0920731

5

教授 - 義守大學生物科技學系

0970201 - 1020201

6

教授 - 義守大學醫學管理學系

0960201 - 0970131

7

副教授 - 義守大學醫學管理學系

0940201 - 0960131

8

副教授 - 義守大學通識教育中心

0930407 - 0940131

 

研究專長:

  癌腫瘤學、分子生物學、婦產科學

 

期刊論文:

西元年-作者別-職號 yyyy/author order/employee no

收錄類別 - 發表期刊 - 期刊簡稱category/journal name/journal abbreviation

卷期頁數 - Impact Factor volume, issue & page no/impact factor

期刊排名-領域期刊數-排名% journal ranking/number of journals of this field/ranking%

中英文題名 - 作者 title(Chinese & English)/author

汪硯雲#,王文岑#,蘇昶瑋,許經偉,袁行修*,陳玉昆* - Overexpression of sprouty 1 protein in human oral squamous cell carcinogenesis. - 1 - Journal of dental sciences - JOURNAL OF DENTAL SCIENCES 2021 16(1):21-28 1.034 83 - 91 - 91.21%
Yen-Yun Wang#,Wen-Chen Wang#,Chiang-Wei Su,Ching-Wei Hsu,Shyng-Shiou Yuan,Yuk-Kwan Chen* - Overexpression of sprouty 1 protein in human oral squamous cell carcinogenesis. - 1 - Journal of dental sciences - JOURNAL OF DENTAL SCIENCES 2021;16(1):21-28 1.034 83 - 91 - 91.21%

汪硯雲#,洪純道,StevenLo*,袁行修* - Adipocytokines visfatin and resistin in breast cancer: Clinical relevance, biological mechanisms, and therapeutic potential - 1 - Cancer Letters - CANCER LETTERS 2021 498(-):229-239 7.36 30 - 244 - 12.30%
Yen-Yun Wang, Amos C. Hung, Steven Lo*, Shyng-Shiou F. Yuan*# - Adipocytokines visfatin and resistin in breast cancer: Clinical relevance, biological mechanisms, and therapeutic potential - 1 - Cancer Letters - CANCER LETTERS 2021;498(-):229-239 7.36 30 - 244 - 12.30%

汪硯雲,方本詞#,蘇昶瑋,陳玉昆,黃志中,黃旼儀*,袁行修* - Excision repair cross-complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence - 1 - Oncology Letters - ONCOLOGY LETTERS 2021 21(6):450 2.967 184 - 242 - 76.03%
Yen-Yun Wang, Pen-Tzu Fang#, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang*, Shyng-Shiou F. Yuan* - Excision repair cross-complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence - 1 - Oncology Letters - ONCOLOGY LETTERS 2021;21(6):450 2.967 184 - 242 - 76.03%

汪硯雲,陳玉昆,StevenLo,紀宗辰,陳怡華,胡楚松,陳雅雯,江士昇,蔡芳瑜,劉旺達,李瑞年,謝雅晶,黃志仁,袁行修* - MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner. - 1 - Oncogene - ONCOGENE 2021 40(20):3510-3532 9.867 29 - 298 - 9.73%
Yen-Yun Wang, Yuk-Kwan Chen, Steven Lo, Tsung-Chen Chi, Yi-Hua Chen, Stephen Chu-Sung Hu, Ya-Wen Chen, Shih Sheng Jiang, Fang-Yu Tsai, Wangta Liu, Ruei-Nian Li, Ya-Ching Hsieh, Chih-Jen Huang, Shyng-Shiou F Yuan* - MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner. - 1 - Oncogene - ONCOGENE 2021;40(20):3510-3532 9.867 29 - 298 - 9.73%

汪硯雲,洪純道,StevenLo,謝雅晶,袁行修* - MRE11 as a molecular signature and therapeutic target for cancer treatment with radiotherapy. - 1 - Cancer letters - CANCER LETTERS 2021 514(21):1-11 8.679 34 - 242 - 14.05%
Yen-Yun Wang,Amos C Hung,Steven Lo,Ya-Ching Hsieh,Shyng-Shiou F Yuan - MRE11 as a molecular signature and therapeutic target for cancer treatment with radiotherapy. - 1 - Cancer letters - CANCER LETTERS 2021;514(21):1-11 8.679 34 - 242 - 14.05%

Shang-Jung Wu,Arivajiagane Arundhathi,Hsiang-Ching Wang,陳巧雲*,Tsai-MuCheng,袁行修*,王雲銘* - Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies. - 1 - Translational oncology - TRANSLATIONAL ONCOLOGY 2021 14(7):101057 4.243 117 - 242 - 48.35%
Shang-Jung Wu,Arivajiagane Arundhathi,Hsiang-Ching Wang,Chiao-Yun Chen,Tsai-Mu Cheng,Shyng-Shiou F Yuan,Yun-Ming Wang - Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies. - 1 - Translational oncology - TRANSLATIONAL ONCOLOGY 2021;14(7):101057 4.243 117 - 242 - 48.35%

汪硯雲, 蕭綾儀, 吳寶珠, 陳玉昆, Steven Lo, 胡楚松, 陳怡華, 邱建智, 袁行修* - Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo - 1 - Biochemical Pharmacology - BIOCHEMICAL PHARMACOLOGY 2020 171(-):113713 4.96 27 - 271 - 9.96%
Yen Yun Wang, Ling Yi Xiao, Pao Chu Wu, Yuk Kwan Chen, Steven Lo, Stephen Chu Sung Hu, Yi Hua Chen, Charles Chien Chih Chiu, Shyng Shiou F. Yuan* - Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo - 1 - Biochemical Pharmacology - BIOCHEMICAL PHARMACOLOGY 2020;171(-):113713 4.96 27 - 271 - 9.96%

鮑永定#, 汪硯雲#, 陳玉昆, 蘇昶瑋, 許經偉, 蕭綾儀, 袁行修*, 李瑞年* - Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer - 1 - oral diseases - ORAL DISEASES 2020 26(4):756-765 2.613 19 - 91 - 20.88%
Yung‐Ding Bow#, Yen‐Yun Wang#, Yuk‐Kwan Chen, Chang‐Wei Su, Ching‐Wei Hsu, Ling‐yi Xiao, Shyng‐Shiou Yuan*, Ruei‐Nian Li* - Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer - 1 - oral diseases - ORAL DISEASES 2020;26(4):756-765 2.613 19 - 91 - 20.88%

蔡郁棻, 汪硯雲, 袁行修* - Comet tail, an indicator for DNA damage or repair?: Refers to Liu et al. Oral Oncology 2020 Jan;100:104469 - 1 - Oral Oncology - ORAL ONCOLOGY 2020 104(-):104624 3.979 5 - 91 - 5.49%
Yu-Fen Tsai, Yen-Yun Wang, Shyng-Shiou F. Yuan* - Comet tail, an indicator for DNA damage or repair?: Refers to Liu et al. Oral Oncology 2020 Jan;100:104469 - 1 - Oral Oncology - ORAL ONCOLOGY 2020;104(-):104624 3.979 5 - 91 - 5.49%

Anupama Vadhan, 汪硯雲, 袁行修, 李怡琛, 胡楚松, Jyuan-Yuan Huang, Takashi Ishikawa, 侯明鋒* - EMI2 expression as a poor prognostic factor in patients with breast cancer - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2020 36(8):640-648 1.291 114 - 136 - 83.82%
Anupama Vadhan, Yen-Yun Wang, Shyng-Shiou F. Yuan, Yi-Chen Lee, Stephen Chu-Sung Hu, Jyuan-Yuan Huang, Takashi Ishikawa, Ming-Feng Hou* - EMI2 expression as a poor prognostic factor in patients with breast cancer - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2020;36(8):640-648 1.291 114 - 136 - 83.82%

汪硯雲, 蕭綾儀, 陳玉昆, 吳寶珠, 陳怡樺, 胡楚松, 袁行修* - Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo - 1 - ACS Omega - ACS OMEGA 2020 5(12):7018–7024 2.584 76 - 172 - 44.19%
Yen-Yun Wang, Ling-Yi Xiao, Yuk-Kwan Chen, Pao-Chu Wu, Yi-Hua Chen, Stephen Chu-Sung Hu, and Shyng-Shiou F. Yuan* - Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo - 1 - ACS Omega - ACS OMEGA 2020;5(12):7018–7024 2.584 76 - 172 - 44.19%

邱文進#, 方本詞#, 李怡琛, 汪硯雲, 蘇郁涵, 胡楚松, 陳玉昆, 徐雨棠, 高英軒, 黃旼儀*, 袁行修* - DNA repair protein Rad51 induces tumor growth and metastasis in esophageal squamous cell carcinoma via a p38/Akt dependent pathway - 1 - Annals of Surgical Oncology - Ann Surg Oncol 2020 20(20):20 3.681 27 - 203 - 13.30%
Wen-Chin Chiu#, Pen-Tzu Fang#, Yi-Chen Lee, Yen-Yun Wang, Yu-Han Su, Stephen Chu-Sung Hu, Yuk-Kwan Chen, Yu-Tong Tsui, Ying-Hsien Kao, Ming-Yii Huang*, Shyng-Shiou F. Yuan* - DNA repair protein Rad51 induces tumor growth and metastasis in esophageal squamous cell carcinoma via a p38/Akt dependent pathway - 1 - Annals of Surgical Oncology - Ann Surg Oncol 2020;20(20):20 3.681 27 - 203 - 13.30%

楊宜芳, 汪硯雲, 蕭宏昇, Steven Lo, Yu-Chan Chang, Yi-Hua Jan, Tsung-Ching Lai, 李怡琛, Ya-Ching Hsieh, 袁行修* - IMPAD1 Functions as Mitochondrial Electron Transport Inhibitor That Prevents ROS Production and Promotes Lung Cancer Metastasis Through the AMPK-Notch1-HEY1 Pathway - 1 - CANCER LETTERS - CANCER LETTERS 2020 15(485):27-37 6.508 29 - 230 - 12.61%
Yi-Fang Yang, Yen-Yun Wang, Michael Hsiao, Steven Lo, Yu-Chan Chang, Yi-Hua Jan, Tsung-Ching Lai, Yi-Chen Lee, Ya-Ching Hsieh, Shyng-Shiou F Yuan* - IMPAD1 Functions as Mitochondrial Electron Transport Inhibitor That Prevents ROS Production and Promotes Lung Cancer Metastasis Through the AMPK-Notch1-HEY1 Pathway - 1 - CANCER LETTERS - CANCER LETTERS 2020;15(485):27-37 6.508 29 - 230 - 12.61%

余姿蓉, 湯人仰, 歐陽賦, 汪硯雲, 袁行修, Kevin Tseng, Li-Ching Lin*, 張學偉* - Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells - 1 - Biomolecules - BIOMOLECULES 2020 10(5):777 4.879 96 - 298 - 32.21%
Tzu-Jung Yu, Jen-Yang Tang, Fu Ou-Yang, Yen-Yun Wang, Shyng-Shiou F Yuan, Kevin Tseng, Li-Ching Lin*, Hsueh-Wei Chang* - Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells - 1 - Biomolecules - BIOMOLECULES 2020;10(5):777 4.879 96 - 298 - 32.21%

湯人仰, 吳光涵, 汪硯雲, Ammad Ahmad Farooqi, Hurng-Wern Huang, 袁行修, Ru-In Jian, Li-Yi Tsao, Po-An Chen, 張芳榮, 鄭源斌, 胡皓竣*, 張學偉* - Methanol Extract ofUsnea barbataInduces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020 9(8):694 6.312 11 - 144 - 7.64%
Jen-Yang Tang, Kuang-Han Wu, Yen-Yun Wang, Ammad Ahmad Farooqi, Hurng-Wern Huang, Shyng-Shiou F Yuan, Ru-In Jian, Li-Yi Tsao, Po-An Chen, Fang-Rong Chang, Yuan-Bin Cheng, Hao-Chun Hu*, Hsueh-Wei Chang* - Methanol Extract ofUsnea barbataInduces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020;9(8):694 6.312 11 - 144 - 7.64%

王聖傑, 汪硯雲, Li-Ching Lin, 張夢揚, 袁行修, 湯人仰*, 張學偉* - Combined Treatment of Sulfonyl Chromen-4-Ones (CHW09) and Ultraviolet-C (UVC) Enhances Proliferation Inhibition, Apoptosis, Oxidative Stress, and DNA Damage against Oral Cancer Cells. - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21(17):6443 5.923 67 - 298 - 22.48%
Sheng-Chieh Wang, Yen-Yun Wang, Li-Ching Lin, Meng-Yang Chang, Shyng-Shiou F Yuan, Jen-Yang Tang*, Hsueh-Wei Chang* - Combined Treatment of Sulfonyl Chromen-4-Ones (CHW09) and Ultraviolet-C (UVC) Enhances Proliferation Inhibition, Apoptosis, Oxidative Stress, and DNA Damage against Oral Cancer Cells. - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(17):6443 5.923 67 - 298 - 22.48%

汪硯雲,陳奐達,StevenLo,陳玉昆,黃鈺淇,胡楚松,謝雅晶,洪純道,侯明鋒,袁行修* - Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages - 1 - Cancers - CANCERS 2020 12(12):2020 Nov 26;12(12):E3526 6.126 37 - 244 - 15.16%
Yen-Yun Wang #, Huan-Da Chen , Steven Lo , Yuk-Kwan Chen , Yu-Ci Huang , Stephen Chu-Sung Hu , Ya-Ching Hsieh , Amos C Hung , Ming-Feng Hou , Shyng-Shiou F Yuan* - Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages - 1 - Cancers - CANCERS 2020;12(12):2020 Nov 26;12(12):E3526 6.126 37 - 244 - 15.16%

彭聖堯, 汪硯雲, 藍鼎勳, 林立青, 袁行修, 湯人仰*, 張學偉* - Low Dose Combined Treatment with Ultraviolet-C and Withaferin a Enhances Selective Killing of Oral Cancer Cells - 1 - Antioxidants (Basel) - ANTIOXIDANTS 2020 9(11):1120 6.312 11 - 144 - 7.64%
Sheng-Yao Peng, Yen-Yun Wang, Ting-Hsun Lan, Li-Ching Lin, Shyng-Shiou F Yuan, Jen-Yang Tang*, Hsueh-Wei Chang* - Low Dose Combined Treatment with Ultraviolet-C and Withaferin a Enhances Selective Killing of Oral Cancer Cells - 1 - Antioxidants (Basel) - ANTIOXIDANTS 2020;9(11):1120 6.312 11 - 144 - 7.64%

陳丙何, 鍾加明, 汪硯雲, 黃弘文, 黃斌, 李家和, 袁行修, 吳哲維, 林莉萱, 曾良鵬* - CYP26A1新穎標記與檳榔相關口腔及咽癌 - 1 - Diagnostics (Basel, Switzerland) - DIAGNOSTICS 2020 10(11):982 3.706 45 - 169 - 26.63%
Ping-Ho Chen, Chia-Min Chung, Yen-Yun Wang, Hurng-Wern Huang, Bin Huang, Ka-Wo Lee, Shyng-Shiou Yuan, Che-Wei Wu, Lee-Shuan Lin, Leong-Perng Chan* - CYP26A1 Is a Novel Biomarker for Betel Quid-Related Oral and Pharyngeal Cancers. - 1 - Diagnostics (Basel, Switzerland) - DIAGNOSTICS 2020;10(11):982 3.706 45 - 169 - 26.63%

黃志仁,黃旼儀,方本詞,陳韋廷, 王昱蒼,陳中和,袁行修, 黃鈞民, 羅逵皓, 莊弘毅, 汪硯雲, 李欣樺* - Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients - 1 - American Journal of Clinical Nutrition - AMERICAN JOURNAL OF CLINICAL NUTRITION 2019 109(3):606-614 6.766 6 - 89 - 6.74%
Chih-Jen Huang, Ming-Yii Huang, Pen-Tzu Fang, Frank Chen, Yu-Tsang Wang, Chung-Ho Chen, Shyng-Shiou Yuan, Chun-Ming Huang, Kuei-Hau Luo, Hung-Yi Chuang, Yen-Yun Wang, and Hsin-Hua Lee* - Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients - 1 - American Journal of Clinical Nutrition - AMERICAN JOURNAL OF CLINICAL NUTRITION 2019;109(3):606-614 6.766 6 - 89 - 6.74%

汪硯雲, 陳玉昆, 胡楚松, 蕭綾儀, 黃婉綾, 紀宗辰, 鄭光宏, 王雲銘*, 袁行修* - MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death - 1 - Oral Diseases - ORAL DISEASES 2019 25(3):758-771 2.613 19 - 91 - 20.88%
Wang YY, Chen YK, Hu CS, Xiao LY, Huang WL, Chi TC, Cheng KH, Wang YM*, Yuan SF* - MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death - 1 - Oral Diseases - ORAL DISEASES 2019;25(3):758-771 2.613 19 - 91 - 20.88%

王耀廣,陳威昌(共同第一),賴瑩荷, 陳以勳,吳明蒼,郭啟東,汪硯雲, 袁行修, 劉于鵬*,吳宜珍* - Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer - 1 - Cancers (Basel) - Cancers (Basel) 2019 11(3):E387 5.326 45 - 223 - 20.18%
Wang YK, Chen WC, Lai YH, Chen YH, Wu MT, Kuo CT, Wang YY, Yuan SF, Liu YP, Wu IC* - Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer - 1 - Cancers (Basel) - Cancers (Basel) 2019;11(3):E387 5.326 45 - 223 - 20.18%

李怡琛,林俊祐,陳彥旭,邱文進,汪硯雲,許勤,胡楚松,袁行修* - Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20(-):1687 4.556 74 - 297 - 24.92%
YC Lee, CY Lin,YH Chen,WC Chiu,YY Wang, C Hsu ,CS Hu, YH Su,SS Yuan* - Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(-):1687 4.556 74 - 297 - 24.92%

胡楚松, 袁行修, 陳國熏, 杜鴻賓* - Increased incidence of ischaemic heart disease and cerebrovascular disease in psoriasis patients with depression: A nationwide retrospective cohort study - 1 - Journal of the European Academy of Dermatology and Venereology - JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 2019 33(8):1547-1554 5.248 5 - 68 - 7.35%
Hu SC, Yuan SF, Chen GS, Tu HP*. - Increased incidence of ischaemic heart disease and cerebrovascular disease in psoriasis patients with depression: A nationwide retrospective cohort study - 1 - Journal of the European Academy of Dermatology and Venereology - JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 2019;33(8):1547-1554 5.248 5 - 68 - 7.35%

黃志仁,黃旼儀,石明誠,鄭凱元,李家和,呂姿瑩,袁行修,方本詞* - Post-radiation sinusitis is associated with recurrence in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy - 1 - Radiation oncology - RADIATION ONCOLOGY 2019 14(1):61 2.817 47 - 133 - 35.34%
Chih-Jen Huang,Ming-Yii Huang,Ming-Chen Paul Shih,Kai-yuan Cheng,Ka-Wo Lee,Tzu-Ying Lu,Shyng-Shiou Yuan,Pen-Tzu Fang* - Post-radiation sinusitis is associated with recurrence in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy - 1 - Radiation oncology - RADIATION ONCOLOGY 2019;14(1):61 2.817 47 - 133 - 35.34%

楊宜芳,李怡琛,汪硯雲,王啟鴻,侯明鋒,袁行修* - YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells. - 1 - Kaohsiung J Med Sci. - Kaohsiung J Med Sci 2019 2019(2019):1-9 1.288 110 - 133 - 82.71%
Yang YF, Lee YC, Wang YY, Wang CH, Hou MF, Yuan SF*. - YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells. - 1 - Kaohsiung J Med Sci. - Kaohsiung J Med Sci 2019;2019(2019):1-9 1.288 110 - 133 - 82.71%

黃建喬#, 鄭凱文#, 謝元欽, 林文瑋, 鄭秋敏, 袁行修, 陳怡如, 鄭以安, 黃柏誠, 呂韻綺, 董宜青*, 鄭添祿* - Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein - 1 - Scientific Reports - SCIENTIFIC REPORTS 2019 9(1):9931 3.998 17 - 71 - 23.94%
Huang CC, Cheng KW, Hsieh YC, Lin WW, Cheng CM, Yuan SS, Chen IJ, Cheng YA, Huang BC, Lu YC, Tung YC*, Cheng TL* - Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein - 1 - Scientific Reports - SCIENTIFIC REPORTS 2019;9(1):9931 3.998 17 - 71 - 23.94%

Hui-Ru Wang,湯人仰, 汪硯雲, Ammad Ahmad Farooqi, Ching-Yu Yen, 袁行修, 黃弘文*, 張學偉* - Manoalide preferentially provides antiproliferation of oral cancer cells by oxidative stress-mediated apoptosis and DNA damage - 1 - Cancers - CANCERS 2019 11(9):1303 6.126 37 - 244 - 15.16%
Hui-Ru Wang, Jen-Yang Tang, Yen-Yun Wang, Ammad Ahmad Farooqi, Ching-Yu Yen, Shyng-Shiou F. Yuan, Hurng-Wern Huang*, Hsueh-Wei Chang* - Manoalide preferentially provides antiproliferation of oral cancer cells by oxidative stress-mediated apoptosis and DNA damage - 1 - Cancers - CANCERS 2019;11(9):1303 6.126 37 - 244 - 15.16%

張文燦, Chang-Yi Wu, 林盈廷, Min-Tsui Wu, Kai-Li Su, 袁行修, Hui-Min David Wang, Yao Fong, Yi-Hsiung Lin*, 邱建智* - C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20(17):4292 4.556 74 - 297 - 24.92%
Wen-Tsan Chang, Chang-Yi Wu, Yin-Chieh Lin, Min-Tsui Wu, Kai-Li Su, Shyng-Shiou Yuan, Hui-Min David Wang, Yao Fong, Yi-Hsiung Lin*, Chien-Chih Chiu* - C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(17):4292 4.556 74 - 297 - 24.92%

Chien-Chiao Huang#, Kai-Wen Cheng#, Yuan-Chin Hsieh, Wen-Wei Lin, Chiu-Min Cheng, 袁行修, 陳怡如, Yi-An Cheng, Yun-Chi Lu, Bo-Cheng Huang, 董宜青*, 鄭添祿* - Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein. - 1 - Scientific Reports - Sci Rep 2019 9(-):9931 4.011 15 - 69 - 21.74%
Chien-Chiao Huang#, Kai-Wen Cheng#, Yuan-Chin Hsieh, Wen-Wei Lin, Chiu-MinCheng, Shyng-Shiou F.Yuan, I-Ju Chen, Yi-An Cheng, Yun-Chi Lu, Bo-Cheng Huang, Yi-ChingTung*, Tian-LuCheng* - Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein. - 1 - Scientific Reports - Sci Rep 2019;9(-):9931 4.011 15 - 69 - 21.74%

Yu-Jen Chen, Shou-Cheng Wu, Hsiang-Ching Wang, Tung-Ho Wu, 袁行修*, Tsai-Te Lu*, Wen-Feng Liaw*, 王雲銘* - Activation of Angiogenesis and Wound Healing in Diabetic Mice Using NO-Delivery Dinitrosyl Iron Complexes - 1 - MOLECULAR PHARMACEUTICS - Mol Pharm 2019 16(10):4241-4251 4.396 39 - 267 - 14.61%
Yu-Jen Chen, Shou-Cheng Wu, Hsiang-Ching Wang, Tung-Ho Wu, Shyng-Shiou F. Yuan*, Tsai-Te Lu*, Wen-Feng Liaw*, Yun-Ming Wang* - Activation of Angiogenesis and Wound Healing in Diabetic Mice Using NO-Delivery Dinitrosyl Iron Complexes - 1 - MOLECULAR PHARMACEUTICS - Mol Pharm 2019;16(10):4241-4251 4.396 39 - 267 - 14.61%

黃俊淵, 汪硯雲, Steven Lo, Ling-Ming Tseng, Dar-Ren Chen, 吳益嘉, 侯明鋒, 袁行修* - Visfatin mediates malignant behaviors through adipose-derived stem cells intermediary in breast cancer - 1 - Cancers (Basel) - CANCERS 2019 12(1):29 6.126 37 - 244 - 15.16%
Jyun-Yuan Huang, Yen-Yun Wang, Steven Lo, Ling-Ming Tseng, Dar-Ren Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F. Yuan * - Visfatin mediates malignant behaviors through adipose-derived stem cells intermediary in breast cancer - 1 - Cancers (Basel) - CANCERS 2019;12(1):29 6.126 37 - 244 - 15.16%

王啟鴻,王柏人,謝雅晶,S Lo,李怡琛,陳月秋,蔡駿豪,邱文進,胡楚松,呂淳雯,楊宜芳,邱建智,歐陽賦,王雲銘,侯明鋒,袁行修* - Resistin facilitates breast cancer progression via TLR4-mediated induction of mesenchymal phenotypes and stemness properties - 1 - Oncogene - ONCOGENE 2018 37(5):589-600 6.854 15 - 163 - 9.20%
Wang CH, Wang PJ, Hsieh YC, Lo S, Lee YC, Chen YC,Tsai CH,Chiu WC, Chu-Sung Hu,Lu CW,Yang YF,Chiu CC,Ou-Yang Fu, Wang YM, Hou MF, Yuan SS* - Resistin facilitates breast cancer progression via TLR4-mediated induction of mesenchymal phenotypes and stemness properties - 1 - Oncogene - ONCOGENE 2018;37(5):589-600 6.854 15 - 163 - 9.20%

魏芯樺,李怡琛(共同第一), Li‑Yeh Chuang,袁行修,歐陽賦,侯明鋒,楊正宏*,張學偉* - Cumulative receiver operating characteristic for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression - 1 - Cancer Cell International - CANCER CELL INT 2018 18(1):19 3.96 73 - 222 - 32.88%
Sin‑Hua Moi†, Yi‑Chen Lee† (co-first), Li‑Yeh Chuang, Shyng‑Shiou F. Yuan, Fu Ou‑Yang, Ming‑Feng Hou, Cheng‑Hong Yang*, Hsueh‑Wei Chang* - Cumulative receiver operating characteristic for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression - 1 - Cancer Cell International - CANCER CELL INT 2018;18(1):19 3.96 73 - 222 - 32.88%

楊宜芳,李怡琛,勞志祥,鍾怡寧,謝雅晶,邱文進,袁行修* - A positive feedback loop of IL-17B-IL-17RB activates ERK/β-catenin to promote lung cancer metastasis - 1 - Cancer Letters - Cancer Lett  2018 422(-):44-55 6.491 28 - 222 - 12.61%
Yang YF, Lee YC, Lo S, Chung YN, Hsieh YC, Chiu WC, Yuan SF* - A positive feedback loop of IL-17B-IL-17RB activates ERK/β-catenin to promote lung cancer metastasis. - 1 - Cancer Letters - Cancer Lett  2018;422(-):44-55 6.491 28 - 222 - 12.61%

廖倍顯,#汪硯雲#,王文岑#,陳中和,高郁勳,許經偉,陳靜怡,陳丙何,袁行修*,陳玉昆* - Overexpression of sprouty2 in human oral squamous cell carcinog enesis. - 1 - Archives of Oral Biology - Arch Oral Biol 2018 87(2018):131-142 2.05 28 - 91 - 30.77%
Liao PH#, Wang YY#, Wang WC#, Chen CH, Kao YH, Hsu JW, Chen CY, Chen PH, Yuan SS, Chen YK. - Overexpression of sprouty2 in human oral squamous cell carcinog enesis. - 1 - Archives of Oral Biology - Arch Oral Biol 2018;87(2018):131-142 2.05 28 - 91 - 30.77%

張學偉, 顏欽堉, 陳中和, 蔡閏旭, 湯人仰, YUNG-TING CHANG, 高郁勛, 汪硯雲, 袁行修,SHENG-YANG LEE* - Evaluation of the mRNA expression levels of integrins α3, α5, β1 and β6 as tumor biomarkers of oral squamous cell carcinoma - 1 - Oncology Letters - Oncol Lett 2018 16(16):4773-4781 1.664 49 - 222 - 22.07%
HSUEH-WEI CHANG, CHING-YU YEN, CHUNG-HO CHEN ,JUN-HSU TSAI , JEN-YANG TANG, YUNG-TING CHANG, YU-HSUN KAO, YEN-YUN WANG, SHYNG-SHIOU F. YUAN,SHENG-YANG LEE* - Evaluation of the mRNA expression levels of integrins α3, α5, β1 and β6 as tumor biomarkers of oral squamous cell carcinoma - 1 - Oncology Letters - Oncol Lett 2018;16(16):4773-4781 1.664 49 - 222 - 22.07%

Lee M, Palanisamy S, Zhou BH, Wang LY,陳巧雲, Lee CY,袁行修*,王雲銘*. - Ultrasensitive Electrical Detection of Follicle Stimulating Hormone Using Functionalized Silicon Nanowire Transistor Chemosensor. - 1 - ACS Applied Materials & Interfaces - ACS Appl Mater Interfaces 2018 10(-):36120-36127 8.097 26 - 285 - 9.12%
Lee M, Palanisamy S, Zhou BH, Wang LY, Chen CY, Lee CY, Yuan SF, Wang YM. - Ultrasensitive Electrical Detection of Follicle Stimulating Hormone Using Functionalized Silicon Nanowire Transistor Chemosensor. - 1 - ACS Applied Materials & Interfaces - ACS Appl Mater Interfaces 2018;10(-):36120-36127 8.097 26 - 285 - 9.12%

張由俐,馮瑤,蔡英美,張雅晶,周翰林,吳長益,鄧燕妮,TC Liu,袁行修, 邱建智* - Exogenous C8-ceramide induces apoptosis by over-production of ROS and the switch of superoxide dismutases SOD1 to SOD2 in human lung cancer cells. - 1 - International Journal of Molecular Sciences - Int. J. Mol. Sci. 2018 19(10):3010 4.183 78 - 297 - 26.26%
YC. Chang, Y Fong, EM Tsai, YG Chang, HL Chou, CY Wu, YN Teng, TC Liu, SS Yuan, Chien-Chih Chiu* - Exogenous C8-ceramide induces apoptosis by over-production of ROS and the switch of superoxide dismutases SOD1 to SOD2 in human lung cancer cells. - 1 - International Journal of Molecular Sciences - Int. J. Mol. Sci. 2018;19(10):3010 4.183 78 - 297 - 26.26%

呂淳雯, 羅伊絢, 陳珠璜, Lin CY,蔡駿豪, Chen PJ, 楊宜芳, 王啟鴻,譚俊祥,侯明鋒*,袁行修*. - VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis. - 1 - Cancer Letters  - Cancer Lett. 2017 388(2017):130-138 6.375 25 - 217 - 11.52%
Lu CW, Lo YH, Chen CH, Lin CY, Tsai CH, Chen PJ, Yang YF, Wang CH, Tan CH, Hou MF, Yuan SF*. - VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis. - 1 - Cancer Letters  - Cancer Lett. 2017;388(2017):130-138 6.375 25 - 217 - 11.52%

楊正宏, Sin-Hua Moi, Li-Yeh Chuang,袁行修,侯明鋒,李怡琛*,張學偉* - Interaction of MRE11 and clinicophathological characteristics in recurrence of breast cancer: Individual and cumulated receiver operating characteristic analyses - 1 - BioMed Research International - Biomed Res Intl 2017 2017(1):2563910(1-9) 2.476 67 - 160 - 41.88%
Cheng-Hong Yang, Sin-Hua Moi, Li-Yeh Chuang, Shyng-Shiou F. Yuan, Ming-Feng Hou, Yi-Chen Lee*, Hsueh-Wei Chang* - Interaction of MRE11 and Clinicopathologic Characteristics in Recurrence of Breast Cancer: Individual and Cumulated Receiver Operating Characteristic Analyses. - 1 - BioMed Research International - Biomed Res Intl 2017;2017(1):2563910(1-9) 2.476 67 - 160 - 41.88%

蔡駿豪,洪純道(共同第一),陳媛盈,邱雅雯,謝沛文,李怡琛,蘇郁涵,PC Chang,胡楚松,袁行修* - 3'-hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction. - 1 - Oncotarget  - Oncotarget 2017 8(-):18106-18117 5.168 44 - 217 - 20.28%
Chun-Hao Tsai*, Amos C. Hung*, Yuan-Yin Chen, Ya-Wen Chiu, Pei-Wen Hsieh, Yi-Chen Lee, Yu-Han Su, Po-Chih Chang, Stephen Chu-Sung Hu, Shyng-Shiou F. Yuan* - 3'-hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction. - 1 - Oncotarget  - Oncotarget 2017;8(-):18106-18117 5.168 44 - 217 - 20.28%

蔡駿豪, 謝沛文,李怡琛,王啟鴻,邱文進,呂淳雯,汪硯雲,胡楚松, 鄭添祿, 袁行修* - 3'-Hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells - 1 - LIFE SCIENCES - MEDICINE, RESEARCH & EXPERIMENTAL  2017 172(2017):19-26 2.936 45 - 128 - 35.16%
Tsai CH, Hsieh PW, Lee YC, Wang CH, Chiu WC, Lu CW, Wang YY, Hu SC, Cheng TL, Yuan SF* - 3'-Hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells - 1 - LIFE SCIENCES - MEDICINE, RESEARCH & EXPERIMENTAL  2017;172(2017):19-26 2.936 45 - 128 - 35.16%

黃則達,黃振勳,汪硯雲,陳坤仲,王東堯,陳怡君,吳哲維,曾良鵬,林奕筑,高郁勛,二岡祥子,袁行修*,詹寶珠* - Novel quantitative analysis of autofluorescence images for oral cancer screening. - 1 - Oral Oncol - ORAL ONCOL 2017 68(-):20-26 4.794 1 - 90 - 1.11%
Huang TT, Huang JS, Wang YY, Chen KC, Wong TY, Chen YC, Wu CW, Chan LP, Lin YC, Kao YH, Nioka S, Yuan SF*, Chung PC*. - Novel quantitative analysis of autofluorescence images for oral cancer screening. - 1 - Oral Oncol - ORAL ONCOL 2017;68(-):20-26 4.794 1 - 90 - 1.11%

汪硯雲,陳玉昆,許雅玲,邱文進,蔡峻豪,胡楚松,謝佩文,袁行修* - Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction. - 1 - Head Neck - Head Neck 2017 39(6):1055-1064 3.376 1 - 42 - 2.38%
Wang YY, Chen YK, Hsu YL, Chiu WC, Tsai CH, Hu SC, Hsieh PW, Yuan SF. - Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction. - 1 - Head Neck - Head Neck 2017;39(6):1055-1064 3.376 1 - 42 - 2.38%

汪硯雲,陳玉昆,胡楚松,許雅玲,蔡峻豪,紀宗辰,謝佩文,袁行修* - CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis. - 1 - CANCER CHEMOTHERAPY AND PHARMACOLOGY - CANCER CHEMOTH PHARM 2017 79(6):1129-1140 2.737 112 - 256 - 43.75%
Wang YY, Chen YK, Hu SC, Hsu YL, Tsai CH, Chi TC, Huang WL, Hsieh PW, Yuan SF* - CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis. - 1 - CANCER CHEMOTHERAPY AND PHARMACOLOGY - CANCER CHEMOTH PHARM 2017;79(6):1129-1140 2.737 112 - 256 - 43.75%

曹俊傑,湯謹如(共同第一),周翰林,Chun-Yen Liu,Ming-Chong Ng,張雨婷,袁行修,蔡英美,邱建智* - The Potential Role of Krüppel-Like Zinc Finger Protein Glis3 in Genetic Diseases and Cancers - 1 - Archivum Immunologiae et Therapiae Experimentalis - 2017 65(5):381-389 2.04 116 - 150 - 77.33%
Chon-Kit Chou,Chin-Ju Tang,Han-Lin Chou,Chun-Yen Liu,Ming-Chong Ng,Yu-Ting Chang,Shyng-Shiou F. Yuan,Eing-Mei Tsai,Chien-Chih Chiu* - The Potential Role of Krüppel-Like Zinc Finger Protein Glis3 in Genetic Diseases and Cancers - 1 - Archivum Immunologiae et Therapiae Experimentalis - 2017;65(5):381-389 2.04 116 - 150 - 77.33%

Ammad Ahmad Farooqi, Chih-Wen Shu, 黃弘文, 王慧如, 張詠婷, Sundas Fayyaz,袁行修, 湯人仰*,張學偉* - TRAIL, Wnt, sonic hedgehog, TGFβ, and miRNA signalings are potential targets for oral cancer therapy - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Int J Mol Sci 2017 18(7):1523 3.226 54 - 166 - 32.53%
Ammad Ahmad Farooqi, Chih-Wen Shu, Hurng-Wern Huang, Hui-Ru Wang, Yung-Ting Chang, Sundas Fayyaz, Shyng-Shiou F. Yuan, Jen-Yang Tang*, Hsueh-Wei Chang* - TRAIL, Wnt, sonic hedgehog, TGFβ, and miRNA signalings are potential targets for oral cancer therapy - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Int J Mol Sci 2017;18(7):1523 3.226 54 - 166 - 32.53%

邱文進,李彥龍(共同第一),周世華,李怡琛,蘇郁涵, Hou YA,姜宏興,尹莘玲,胡楚松,黃旼儀,黃志仁*,袁行修*. - Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence. - 1 - Journal of Thoracic Disease - J Thorac Dis 2017 9(8):2498-2509 2.365 36 - 59 - 61.02%
Chiu WC, Lee YL, Chou SH, Lee YC, Su YH, Hou YA, Chiang HH, Yin HL, Hu SC, Huang MY, Huang CJ*, Yuan SF*. - Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence. - 1 - Journal of Thoracic Disease - J Thorac Dis 2017;9(8):2498-2509 2.365 36 - 59 - 61.02%

黃英峰,邱文進,周世華,蘇郁涵,陳毓雯,蔡志仁,黃志仁,黃旼儀,袁行修, 李怡琛*. - Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax. - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES  - Kaohsiung J. Med. Sci 2017 33(1):17-23 1.15 103 - 128 - 80.47%
Huang YF, Chiu WC, Chou SH, Su YH, Chen YW, Chai CY, Huang CJ, Huang MY, Yuan SF, Lee YC*. - Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax. - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES  - Kaohsiung J. Med. Sci 2017;33(1):17-23 1.15 103 - 128 - 80.47%