1

研發長（Provost）：

許雅玲 教授（Prof. Ya-Ling Hsu）

 

聯絡方式：

　電話 (Tel)：886-7-312-1101 分機：2300

　傳真 (FAX)：886-7-321-0701

　 E-mail: yainghsu@kmu.edu.tw

    807高雄市十全一路100號勵學大樓三樓研究發展處

　 No.100,Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

 

現任：

     高雄醫學大學研究發展處 研發長 (2024/8~)

     高雄醫學大學醫學研究所 教  授 (2014/2~)

 

 學歷：

　      高雄醫學大學  天然藥物研究所  博士 

   經歷：

1

教授 Professor - 醫學研究所 Graduate Institute of Medicine

1030801 -

2

副教授 Professor - 醫學研究所 Graduate Institute of Medicin

1000801 - 1030731 

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助理教授 Professor - 醫學研究所 Graduate Institute of Medicin

0970801 - 1000731 

 

研究專長:

分子藥理學、分子生物學、細胞生物學、天然物活性評估

 

期刊論文:

近期著作： 

 1.Hsu YL, Hung JY, Chang WA, Jian SF, Lin YS, Pan YC, Wu CY, Kuo PL*. Hypoxic lung    cancer-derived extracellular vesicle miR-103a increases the oncogenic effects of tumor    associated macrophages by targeting PTEN. Molecular Therapy 2018 Feb 7;26(2):582-    92. (SCI; IF=7.008)

2.Hsu YL, Hung JY, Chang WA, Lin YS, Pan YC, Tsai PH, Wu CY, Kuo PL*. Hypoxic lung    cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability      by targeting prolyl hydroxylase and tight junction protein ZO-1. Oncogene 2017 Aug        24;36(34):4929-42. (SCI; IF=6.854)

3.Hsu YL, Hung JY, Chou SH, Huang MS, Tsai MJ, Lin YS, Chiang SY, Ho YW, Wu CY, Kuo  PL*. Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ    and decreasing Cyr61 expression. Oncogene 2015 Jul 30;34(31):4056-68. (SCI;        IF=6.854)

4.Kuo PL, Huang MS, Hung JY, Chou SH, Chiang SY, Huang YF, Yang CJ, Tsai MJ, Chang  WA, Hsu YL*. Synergistic effect of lung tumor-associated dendritic cell-derived HB-EGF    and CXCL5 on cancer progression. International Journal of Cancer 2014 Jul      1;135(1):96-108. (SCI; IF=7.360)

5.Hsieh CJ, Kuo PL, Hsu YC, Huang YF, Tsai EM*, Hsu YL*. Arctigenin, a dietary            phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells        through the ROS/p38 MAPK pathway and epigenetic regulation. Free Radical Biology &      Medicine 2014 Feb;67:159-70. (SCI; IF=6.020)

6.Hsu YL*, Hou MF, Kuo PL, Huang YF, and Tsai EM. Breast tumor-associated      osteoblast-  derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail  signaling pathway. Oncogene 2013 Sep 12;32(37):4436-47. (SCI; IF=6.854)